Doesn't take too many days at 100% before potentially fatal lung damage starts to show up. Don't worry about that, unless you wake up and find yourself on a ventilator.
Potentially Harmful Effects of Excessive Oxygen and HyperoxemiaEponymously named after Paul Bert and James Lorrain Smith, the detrimental effects of hyperbaric oxygen on the central nervous system [32] and pulmonary tissues [33] respectively, were well described in the 19th century. More recently, it has become clear that high concentrations of normobaric oxygen may also be harmful. As the gas exchange interface of the body, it is logical that pulmonary tissue would be one of the tissues at greatest risk of damage from high-inspired oxygen concentrations, and this has been demonstrated in numerous animal and healthy human volunteer studies. [34] The damage caused to pulmonary tissue by excessive oxygen resembles the changes seen in acute respiratory distress syndrome (ARDS); the magnitude of injury is directly related to the concentration of oxygen and duration of exposure. [35,36] Oxygen toxicity is rarely evident when the FIO2 is less than 0.5. [1] As patients with ARDS frequently require an FIO2 greater than 0.5, they are potentially at risk of exacerbating the underlying lung injury. It has been previously reported that positive pressure ventilation with a high FIO2 (0.61–0.93) resulted in specific pathological findings independent of the detrimental effects of the ventilator. [37] Clinically, oxygen toxicity can result in decreased mucociliary transport, [38,39] atelectasis (resulting in ventilation–perfusion mismatching), inflammation, pulmonary edema, and eventually interstitial fibrosis. [35] These pathologies may result in worsening lung function
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