IPIC Message Board - Msg: 2603894

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Biotech / Medical : IPIC

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Aug 15 3:35 PM EST

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To: WeirdPro Randy who wrote (842)	10/31/1997 10:01:00 AM
From: WeirdPro Randy	of 1359

Diet Pills only cause valve disease in 8%! From today's WSJ: <<By Robert Langreth and Laura Johannes Staff Reporters of The Wall Street Journal When the Food and Drug Administration pressed for a recall last month of two diet drugs taken by millions, it cited data from five medical centers showing an alarming rate of heart-valve defects: 32% of the 291 patients tested. But doctors at 21 other medical sites across the country say they're finding a far lower incidence of valve problems. The doctors performed tests on nearly 750 patients after the recall of Redux and Pondimin was announced, and they found possible valve leaks in just 57 of them -- a rate of only 8%. The conflicting data raise the question of whether the FDA and American Home Products Corp., which markets Redux and Pondimin, might have acted prematurely in withdrawing the drugs. And a lower rate, if further research bears it out, would provide some reassurance to former diet-drug users and could reduce American Home's potential legal liability as it fights dozens of lawsuits filed in the days after the recall. The company declined to comment. Like the FDA's study, the new batch of data isn't stringently scientific. Like the FDA, The Wall Street Journal simply surveyed doctors whose data were readily available, and came up with a sample that isn't necessarily representative of all patients who have taken the diet drug.>>

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