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Biotech / Medical : Lidak Pharm. [LDAKA]

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To: Michael Collins who wrote (89)	2/5/1997 3:27:00 PM
From: James Silverman	of 1115

Michael here's a copy of the LDAK/CHIR alliance. I found it on the Excite search engine. Lidak Pharmaceuticals and Chiron SCID model to test HIV vaccines FOR IMMEDIATE RELEASE LIDAK PHARMACEUTICALS AND CHIRON ENTER INTO COLLABORATIVE RESEARCH AGREEMENT ON AIDS La Jolla, California -- March 23, 1992 -- LIDAK Pharmaceuticals (NASDAQ:LDAKU, LDAKA) and Chiron Corporation (NASDAQ:CHIR) have initiated a collaborative research program to test the potential of new immune therapies against AIDS. The studies utilize the proprietary human immune system-reconstituted SCID mouse technology of LIDAK and Chiron's proprietary vaccines directed against certain properties of HIV. In the LIDAK model, mice with severe combined immune deficiency (SCID) are grafted with mature human peripheral blood cells to create hu-PBL-SCID mice. The grafted human cells make these mice susceptible to HIV infection. In previous contract studies, the hu-PBL-SCID mouse model has been shown to be useful for demonstrating the presence or absence of therapeutic efficacy of anti-AIDS compounds in diminishing or halting progression of HIV infection in such mice.

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