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Biotech / Medical : Ligand (LGND) Breakout!
LGND 201.29+0.2%Nov 17 3:59 PM EST

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To: Henry Niman who wrote (28937)6/23/1999 11:05:00 PM
From: WTDEC  Read Replies (4) of 32384
 
Henry, when you get a chance could you please explain what the two percentages after [C.I.] in the following quote means?

"At the initial dose level of 300 mg/m2/day proposed for marketing, Targretin capsules produced at least 50% improvement (partial response or clinical complete response) in 48% (40/84, 95% confidence intervals [C.I.] 37% to 58%) of patients"

Also, it appears to me that approval of Targretin won't quite be the 'slam-dunk' that Panretin gel was. Your thoughts on the chances for approval would be appreciated.

Best regards,

Walter
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