Major shareholders.
PERCENTAGE OWNED (1) ------------------------ BEFORE AFTER NAME AND ADDRESS OF BENEFICIAL OWNERS SHARES (1) OFFERING OFFERING ----------------------------------------------------- ----------- ----------- Warburg, Pincus Ventures, L.P. (2)........ 3,661,638 44.9 466 Lexington Avenue New York, NY 10017 LF SL Holding LLC (3)..................... 555,555 6.9 30 Rockefeller Plaza, 62(nd) Floor New York, NY 10020 Sheryle J. Bolton (4)..................... 349,999 4.2 Dr. Michael M. Merzenich (5).............. 670,574 8.3 Dr. Paula A. Tallal (6)................... 803,843 10.0 Frank M. Mattson (7)...................... 73,999 * Dr. William M. Jenkins.................... 565,022 7.0 Diane H. Church (8)....................... 35,666 * James A. Mills (9)........................ 20,332 * Carleton A. Holstrom (10)................. 194,449 2.4 Rodman W. Moorhead, III (2)(11)........... 3,661,638 44.9 Dr. Leonard S. Schleifer.................. 52,941 * James E. Thomas (2)(11)................... 3,661,638 44.9 David A. Tanner (12)...................... 555,555 6.9 All directors and executive officers as a group (12 persons) (13)... 6,984,068 80.7
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