VaxGen Inc.-The 1st AIDS Vaccine in Phase 3 HumanTrials Message Board

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Biotech / Medical : VaxGen Inc.-The 1st AIDS Vaccine in Phase 3 HumanTrials

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To: wiz who wrote (67)	7/7/1999 5:58:00 PM
From: GPSite	of 250

Why is VaxGen such a stealth company? It is a long story that boils down to 3 issues: 1) Dr. Don Francis is controversial; 2) AIDS activists do not support vaccine research; and, 3)Many scientists believe that in theory, the approach used by VaxGen (using a cell surface antigen to elicit antibody response)should not -- again, in theory -- be effective against this virus. I can not do these issues justice in this forum all at one time, but if you read The Band Played on by Randy Shilts and go back and find The New York Times Sunday Magazine on which Dr. Francis was the cover story (Don Francis: Saint or Sinner?), you will begin to get an idea of the complexities. As for the antigen-antibody approach used by VaxGen and criticized by others, all one can say is that the detractors cite theory whereas VaxGen cites success in the simian model; success in the phase I and II human trials; and, success in launching a Phase III trial. What have the detractors accomplished thus far with their theories?

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