To all,
found this first report on Usenet:
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Nelfinavir, Saquinavir & Nevirapine RESULTS
From BostonCDS@aol.com
Organization unspecified
Date 22 Mar 1997 08:58:43 -0600
Newsgroups sci.med.aids
Message-ID <43364@sci.med.aids>
One of my best friends got back some amazing results today.
After ONE WEEK on the combo of nelfinavir (Agouron's new protease inhibitor),
saquinavir and nevirapine, his viral load dropped from 170,000 to BELOW
DETECTION of 500 copies, his CD4 absolute count jumped from 97 to 208, and
his CD4% jumped from 5% to 13%.
It is important to know that he has tried and failed the following in the
past two years:
Indinavir (Crixivan), AZT, 3TC, ddI and ddC.
He never could tolerate Ritonavir (Norvir) or D4T.
His dosages were Nefinavir (Viracept) 750 MG x 3, Saquinavir (Invirase) 600
MG x 3,
Nevirapine (Viramune) (regular recommended dosage - can't remember exactly)
THEREFORE, someone who has failed Crixivan (and everything else) can
potentially switch to the recently approved Agouron Protease Inhibitor,
Nelfinavir (Viracept) with Saquinavir and Nevirapine and see AMAZING results.
It's only one anecdote, but it's terrific news if there is not
cross-resistance between the new PI and the older ones!
- David Stokes
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I hope we will see many reports like this (for human reasons)
ps |
