IDPH--Positive preliminary results for pivotal trial of ID Message Board

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Biotech / Medical : IDPH--Positive preliminary results for pivotal trial of ID

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To: Roudy who wrote (1669)	7/14/1999 4:02:00 PM
From: Maurice Winn	1 Recommendation Read Replies (2) of 1762

Incidentally, you might recall over a year ago I reported that a doctor at Scripps Clinic told me he had treated people with Rituxan [this was before February 1998] and had had a couple of cases of tuberculosis from it. I'm interested in the infections resulting from the B-cell depletion Rituxan causes. He also said that in a few years, tuberculosis was likely to become a serious threat with treatment options limited. This antibiotic immunity has been widely reported, but I haven't seen much worry about widespread epidemics of tuberculosis. Have there been reports on these or was this doctor exaggerating about tuberculosis and Rituxan for some reason [perhaps to justify in my mind why he was not offering Rituxan for a CD20 positive intermediate grade NHL]? All I have seen are the boring old reports of people feeling as though they have a bit of influenza. I recall some time that there were some serious side-effects with treatment stopped in some cases. The side-effects would be interesting. Is there a url? Maurice

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