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Biotech / Medical : Biotechnology: The Patenting of DNA

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To: Mike McFarland who wrote (26)7/15/1999 5:05:00 PM
From: Biomaven  Read Replies (1) of 37
 
Mike,

In fact, if I was born with a few genetic flaws that make me
predisposed to a disease, how come the asthma did not
crop up until I was 17? How strange that a person
would develop such a condition at the age when
they are the most healthy--that cant be about genes.


I think the answer to your question lies in the word "predisposition." The key assumption here is that because of your predisposition you are susceptible to some environmental insult that can push you over the edge to a disease state. The insult could presumably be a virus or something much more subtle, like continual stress worrying about biotech nanocaps. <g>

Identical twin studies are revealing here. Occasionally, both twins suddenly develop the same allergy at a similar time late in life. This is probably "predestined," although of course it could be they both got exposed to the same strain of some bug at the same time. More commonly, if one develops something late in life, it is more probable that the other will get it as well, but not definite. (I'm talking common chronic diseases here, not genetic diseases like Huntington's.)

The trouble of course with trying to figure out what SNP's are associated with what diseases is that there is so much noise. One outfit is looking at Iceland, in the hopes that the more genetically homogeneous population there will remove a few degrees of freedom from the equation. Last I heard, Icelanders aren't as genetically homogeneous as they were hoping, even though they apparently all look the same and have the same names. <g>

Peter
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