Monday August 2, 4:30 pm Eastern Time
  Company Press Release
  SOURCE: Pharmacopeia, Inc.
  Pharmacopeia, Inc. Announces 1999 Second Quarter and Six Month Results
  PRINCETON, N.J., Aug. 2 /PRNewswire/ -- Pharmacopeia, Inc. (Nasdaq: PCOP - news) today announced results for the second quarter and six month period ended June 30, 1999. Where applicable, the 1998 results have been restated to reflect the June 1998 acquisition of Molecular Simulations Inc. (MSI), which was accounted for as a pooling of interests.
  Total revenues for the 1999 second quarter were $23.3 million, a 15% increase compared to the $20.3 million reported for the second quarter of 1998. These results include a 23% increase in software segment revenue throughout the United States and Europe and a 17% increase in laboratory services segment revenue. These gains were partially offset by a 29% decrease in software segment revenue in Asia. Total revenues for the six months ended June 30, 1999 rose 14% to $46.6 million compared to $40.8 million reported for the same period last year.
  Net loss for the 1999 second quarter was $1.6 million, or $0.08 per share, compared to a net loss of $8.4 million, or $0.44 per share, for the second quarter of 1998. For the six months ended June 30, 1999, the net loss was $2.2 million, or $0.11 per share, compared to a net loss of $9.2 million, or $0.49 per share, for the comparable six month period of 1998. The net loss for both the 1998 second quarter and the 1998 six month period includes merger-related costs of approximately $8.0 million.
  ''I am pleased to report another quarter of increased revenue,'' stated Joseph A. Mollica, Ph.D., Chairman, President and CEO. ''Our laboratory services segment benefited from activity in our newest collaborations with Schering-Plough, Schering AG and Pharmacia and Upjohn. Research work done on behalf of these new partners, in addition to our existing customers, more than offset the decline in revenues from those partners for whom our work last year has now been successfully completed. Software segment revenues grew 13% despite continued weakness in our sales in Asia. Strong sales in the United States and Europe contributed to our overall gain in this segment. Further, most of the year to date decline in software segment revenue in Asia will be recovered by the end of 1999 as a result of certain performance commitments included in our new Japanese distribution arrangement.''
  ''The second quarter also saw an increased emphasis on our Lead Discovery Services (LDS) business. LDS offers customers access to the unique combination of Pharmacopeia's multi-million compound sample collection and ultra high-throughput screening experience and capacity. Heretofore, we have marketed this business to large pharmaceutical companies. Leveraging MSI's experienced sales force, we began in July to offer this service to the many biotechnology companies who have interesting targets. These companies can benefit from our large chemical sample collection and screening capabilities as well. Given our scientific and technological accomplishments in our drug discovery and software businesses, we remain cautiously optimistic about our overall performance for the remainder of the year,'' concluded Dr. Mollica.
  Pharmacopeia (http://www.pcop.com) is a leader in enabling technology and technology-based services that accelerate drug discovery and chemical development. Pharmacopeia's laboratory services segment (Pharmacopeia Labs) integrates three platform technologies: informatics, small molecule combinatorial chemistry, and high-throughput screening. Using ECLiPSTM, its proprietary combinatorial chemistry technology, Pharmacopeia Labs has generated more than 5.6 million diverse, small molecules. Pharmacopeia Labs tests these molecules using state-of-the-art high-throughput screening. Pharmacopeia's software subsidiary, Molecular Simulations Inc. (MSI), develops and commercializes molecular modeling, simulation, and informatics software and services. The Pharmacopeia Labs and MSI technologies are integrated to support the following four businesses: 1) software sales and service for pharmaceutical, biotechnology, and chemical research, 2) chemical compound leasing, 3) collaborative drug discovery, and 4) internal drug discovery. Pharmacopeia employs approximately 550 people and is headquartered in Princeton, NJ. Major regional operations are in San Diego, CA, Cambridge, England, and Tokyo, Japan.
  Except for the historical information contained herein, this statement may contain projections or other forward-looking statements regarding future events or the future financial performance of the Company. Pharmacopeia wishes to caution you that such statements are just predictions. Actual events or results may differ materially. Pharmacopeia refers you to the documents that it files from time to time with the Securities and Exchange Commission, specifically the Company's last filed Annual Report on Form 10-K and subsequent Quarterly Reports on Form 10-Q. These documents contain and identify important factors, including risk factors that could cause the actual results to differ materially from those contained in the projections or forward-looking statements.
                                  PHARMACOPEIA, INC.                        SELECTED CONSOLIDATED FINANCIAL DATA                (Dollars in thousands, except share data, unaudited)                              Statements of Operations
                                 For the Three Months        For the Six Months                                   Ended June 30,               Ended June 30,                               1999          1998         1999         1998     Revenue:     Contract revenue        $8,228        $7,023      $17,304      $13,455     Software license,      service and other      12,394        11,458       24,817       24,512     Hardware                 2,645         1,814        4,439        2,880     Total revenue           23,267        20,295       46,560       40,847
       Costs and expenses:     Software license      and other                 942           794        2,112        1,563     Hardware                 2,496         1,549        3,973        2,420      Research and      Development     Collaborative            5,092         4,715       10,929        9,135     Proprietary              7,013         7,207       13,710       13,964      Sales, general       and administrative    10,151         8,248       19,768       16,889      Merger related costs       --         7,998           --        7,998     Total costs and      expenses               25,694        30,511       50,492       51,969      Operating loss        (2,427)      (10,216)      (3,932)     (11,122)      Interest and       other income, net        863           907        1,842        1,949      Loss before provision       for (benefit from)       income taxes         (1,564)       (9,309)      (2,090)      (9,173)      Provision for        (benefit from)         income taxes            28         (936)           68          (8)      Net loss             $(1,592)      $(8,373)     $(2,158)     $(9,165)
       Net loss per share        - Basic             $(0.08)       $(0.44)      $(0.11)      $(0.49)      Net loss per share        - Diluted           $(0.08)       $(0.44)      $(0.11)      $(0.49)
       Weighted average number       of common stock     Outstanding - Basic     19,656        18,906       19,465       18,872      Weighted average number       of common stock     Outstanding - Diluted   19,656        18,906       19,465       18,872
                                                       Balance Sheet                                                June 30,       December 31,                                                    1999               1998     Cash, cash equivalents and marketable     securities                                  $63,119            $81,098     Trade receivables, net                       18,888             23,307     Other assets, net                            33,741             23,460     Total assets                               $115,748           $127,865
      Current liabilities                         $42,496            $52,316     Long-term liabilities                         1,337              3,332     Total stockholders' equity                   71,915             72,217     Total liabilities and stockholders'      equity                                    $115,748           $127,865
  SOURCE: Pharmacopeia, Inc.
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