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Biotech / Medical : Sepracor-Looks very promising

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To: j_fir2 who wrote (3536)8/4/1999 7:10:00 PM
From: BMcV  Read Replies (1) of 10280
 
>>I asked Jonae if there were any other ICEs being marketed by other companies. She said that levofloxicin is a single isomer (antibiotic) of offloxicin (sp?) that J&J is marketing. She estimated the market for levofloxicin is $700 million. What they gained with the ICE was more flexibility of usage, better side effect profile, etc. I couldn't find anything resembling offloxicin in the top 200 list at RxList.com--perhaps it is no longer on the market.<<

The parent of Levofloxacin is Levaquin, produced by Ortho-McNeil. Curiously, Levofloxacin is "more active against gram-positive organisms such as S. pneumoniae, including pneumococcal strains highly resistant to penicillin" (quoting from The in-this-instance-deeply-respected Medical Letter). This is evidence that optically-pure versions of existing drugs can have different pharmacological effects than the racemic version.

>>The ICE of thamilomide is used to treat leprosy. Don't know the pharmaceutical company there.<<

Celgene.

>>At home, sick, going through trading files, I see SEPR, 7/27/97, $25.00. Made me feel pretty good to be at $70.<<

Really puts this correction and the initial downsweep in perspective, doesn't it?

Today was eerie. Traded all day in a very narrow range, 69 5/8 to 69 15/16, before the final spike up.

Is it the weekend already?



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