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Biotech / Medical : British Biotech (BBIOY)

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To: Henry Niman who wrote (6)6/3/1996 8:29:00 PM
From: olduser   of 41
 
To all Regarding the Barron's story about Brit. Biotech, Please notice that the parameter used to measure the effectiveness of marimastat is the level of certain proteins. There is no mention of tumor mass reduction (or I guess lack of growth would be more appropriate) or survival rate statistics. On the basis of this article, valid conclusions regarding the effectiveness of the drug can not be drawn. On the upside is the comment about side effects: joint swelling and/or pain will certainly not preclude use in end stage cancer patients. Also, in general an enzyme inhibitor can loose effectiveness in a model where cell turnover and the ablity for mutations are high. I hope to God the drug is good, but more data is needed to form opinions.
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