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Strategies & Market Trends : Biotechnology Cancer Cures

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To: scaram(o)uche who wrote (113)	9/11/1999 11:36:00 PM
From: tnsaf	Read Replies (1) of 226

An interesting item from Bioresearch online. The first bit and link... Jason ---------------------------- Inhibiting p53 May Improve Chemotherapy Outcome 9/9/99 In what might be considered a bold or foolish move, depending on your point of view, scientists from the University of Illinois, Chicago (UIC) and Quark Biotechnologies (Pleasanton, CA) have shut down p53 in mice, and have shown that doing so can protect normal tissues from radiation damage. While the loss of p53 is generally thought to be bad news?over 50% of human tumors lack this protein, whose function is believed to be to rid the body of damaged cells through apoptosis?this group reasoned that its absence might also spare cells from the ravages of radiation and chemotherapy. Work reported in the September 10 issue of Science indicates that their thinking is correct. Mice whose p53 was inhibited withstood lethal doses of radiation, and showed no ill effects of the treatment?that is, no increased incidence of tumors?months after treatment. ---------------------------- www2.bioresearchonline.com{8FCA4AC7-62DC-11D3-9A60-00A0C9C83AFB}&Bucket=Latest+Headlines

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