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Biotech / Medical : COB Columbia Laboratories
COB 14.100.0%Nov 2 5:00 PM EST

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To: wolfdog2 who wrote (588)9/15/1999 10:13:00 AM
From: wolfdog2  Read Replies (1) of 634
 
The following post has an interesting analysis of the trading patterns of biotech companies in relationship to their product cycles. COB was in phase 4 for a long time. Most would say too long. It's now at the beginning of phase 5.

<<To: jeffrey bash (7054 )
From: Harold Engstrom Tuesday, Sep 14 1999 8:06AM ET
Reply # of 7062

Jeffrey, Sepracor has no positive earnings to compliment its pipeline. Other larger cap biotech stocks like Amgen, Biogen, Genentech, Genzyme, Immunex, etc., do have positive earnings as well as promising pipelines.

Lack of earnings makes biotech and pharmaceutical stocks subject to huge earnings swings. The pattern I notice is:

1. IPO, pre-clinical or early clinical: runup in price.
2. Some results: decline in price.
3. More results: no action followed by gradual rise.
4. Approval: runup, then decline.
5. Real earnings: no action, then gradual rise.
6. Significant earnings expansion: gradual PE expansion.

After #6, there is still volatility, but more closely mimicing the market or its sector.

Personally, I think Sepracor is doing pretty well. They are basically at #4 and #5 is still about 2 years out, with #6 apparently following quickly. The company seems to be building a foundation one brick at a time: it has a couple of approvals, fair licensing deals and a very broad pipeline. As Peter has pointed out, their ICE approach appears validated again by CELG's recent results (Ritalin ICE).

Sepracor is one of my favorite stories and I can't believe its not treated like a dot-com.>>

Hey, how about COB.com?

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