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Biotech / Medical : GZMO
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To: scaram(o)uche who wrote (176)12/9/1999 9:32:00 AM
From: jeffbas  Read Replies (1) of 438
 
Rick, nice to see some publicity on something we have known about for some time.

It is my (amateur) understanding that SAGE is the tool that identifies everything that an Affymetrix might want to have on a chip, and that nothing else may do it as completely/cheaply. It is this completeness of identification that I have two questions about for you.

When it is publicly stated that 90% (or whatever large % I have seen in the press) of the human genome has been mapped, with the impression created for people like me that we are almost done, I wonder if this is misleading. Is everything that has been mapped been done with the identification precision that SAGE can do, or is it like a tree -- we have most of the big branches identified but it would take years and massive effort/money with tools like SAGE to identify all the little twigs?

Second question. Is it necessary/desirable to know all the "twigs" in specific disease/drug development research projects?

Thanks for your help.
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