Right now, (given enough money) I could, by myself, develop a gene chip assay for chrom 22 in humans, look at expression levels among different genotypes, and do statistical analyses for the correlation between gene regulation and diseases specific to the 22nd chrom. And I am just one person with limited experience
By the way, what you have described here is a means of identifying a target protein, not a drug. This is, of course, what MLNM does. You still have to design a drug for your target.
God, how many great targets I've seen crash and burn, because the drug entity was too insoluble, metabolically unstable, toxic, had poor pharmicodynamics, wasn't active enough, too much competion to market, too small a target population, and the list goes on.
I almost never give advice, but here's something to really consider. Take some money off the table. Enjoy it. Don't look back 5 years from now and think how much more you could have had if you just held on.
Good Luck! |