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Pastimes : son of T/FIF

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To: JMarcus who wrote (315)	12/15/1999 9:19:00 PM
From: Pseudo Biologist	of 673

Marc, check this: messages.yahoo.com He seems to have direct lab experience with at least some antisense. He makes a good point re. "hit" rates. Some antisense is said to recruit ribonuclease H (? I used to know this stuff) and clip target mRNA as well. I am not sure if the just-failed ISIP compound was supposed to have that property or if it was a simple code blocker. So, no direct answers to your hard questions, oh well. PB

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