This is very important and oh so full of hope!!!
From a presentation by what I think is some sort of research-clinical-scientist
Information from ---VChan
This is proof that LOR may become the block-buster for our new century.
exerpts from lorff ceo annual meeting speech:
GTI twenty-forty has demonstrated outstanding antitumor properties and was shown to be very effective against a wide range of different human cancer lines including the common cancers like lung, breast, colon, liver, kidney and ovary.
I would like to mention that independent toxicology or safety studies indicate that twenty-forty is likely to be safe at doses that exceed those that we expect to use in the up-and-coming clinical trials.
twenty-forty administered in combination with two commonly used anticancer drugs lead to complete tumor regression in all the mice treated. The bars in the graph represent the weight of a human kidney tumor in a mouse model, in an untreated or saline treated solution, treatment with commonly used anticancer drugs alone or with twenty-forty alone.
Notice that when twenty-forty is combined in the treatment schedule with the conventional drugs, complete tumor regression occurs. These rather remarkable results demonstrate the huge potential for using twenty-forty in combination chemotherapy to develop new treatment strategies for cancer patients.
Our second lead compound, GTI twenty five-oh-one, has very dramatic anticancer properties even when used in monotherapy, i.e. when used alone. It is quite rare for any drug to show complete tumor regressions even in combination therapy. It is even rarer to have a drug that is able to completely regress tumors when used alone. Again, the bars represent the weight of the human tumors, breast or kidney derived, in a mouse model.
Treatment with twenty five-oh-one every second day by i.v. (that is, as it is done in the clinic with cancer patients) resulted in the complete loss of tumor in all mice treated. I can tell you that this is a rather spectacular result, and we are anxious to get twenty five-oh-one into toxicology studies and then into clinical trials as quickly as possible.
Treatment with twenty five-oh-one however leads to complete regression of the tumor. Now, if treatment is stopped after 50 days, note that the tumors treated with the well-known drugs begin to accelerate in growth because there is still tumor tissue in these mice. However, in the case where the tumors were treated with twenty five-oh-one, the tumors disappeared and never reappeared after treatment ceased even after we monitored the mice for 46 additional days. Again, these are exceptional results and I think dramatically demonstrate why we are so enthusiastic about getting twenty five-oh-one into clinical trials.
Slides not in my possession.
Expect stock on Monday a.m. to open --DOLLARS---higher!!!!!!!!!!! |
