Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 206.84

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3:59 PM EST

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To: Skeeter Bug who wrote (29987)	1/9/2000 12:10:00 AM
From: Henry Niman	Read Replies (1) of 32384

Speaking of miracles, several years ago a poster on the AOL LGND board indicated that he had bought some LGND because his mother or grandmother had CTCL and treatment with Targretin produced results similar to those described in the testimonials. About the same time there were two newspaper reports on head and neck patients treated with a new drug by LGND (tumors were huge, had not responded to prior treatments, and melted away when treated with Ligand's drug). I had always assume that it was Targretin (one patient was at MD Anderson and the other was at the Lombardi Cancer Center). There wasn't much follow-up and a small head & neck study using Targretin did not produce objective tumor responses. Now that Targretin has been approved, it might be worth dusting off those old reports and revisit use of Targretin for Head & Neck. A few more pieces of anecdotal evidence may go a long way toward off label use of a "newly approved cancer pill".

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