Vion (formerly Oncorx) interesting play on Gene Therapy Message Board

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Biotech / Medical : Vion (formerly Oncorx) interesting play on Gene Therapy

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To: Scott H. Davis who wrote (171)	1/17/2000 9:02:00 PM
From: Jim Oravetz	Read Replies (1) of 370

I liked it much better in $6'ish price range. :) However, as you are aware, lots of biotech stock has rocketed up the last 6 weeks. Money coming from internuts, IMHO. Some pretty good science coming out of Yale here. The home run here is TAPET. De-tox a salmonella bacteria and arm it with a cancer killer. The Sbact. finds the cancer cells and reproduces like crazy. Turn it off with antibiotics. Just started PI, so there is still plenty of time for things to go wrong. Toxicity seems to be reduced enough to make a go of it in PI. Good news re:Promycin. Boringer-Ing. will be paying for and completing of PIII trials. This is for head and neck cancer which I understand is hard to treat. Orphan drug status on this one. These trials have been going on for 1 1/2yr. already - not sure when they are scheduled to end. Look back at some comments from a Q report I made. The freeing of cash is a plus as it gives them longer burn on TAPET and the other drug in development. The other main drug in development, can not remember the name, is also a potential winner. They have licensed a drug that is a synthetic melanin (sp). Although not a block buster, it should give them an income stream that will help keep things going. Overall, some good science here and several paths being pursued. A long way from profitable, with an average burn rate on cash. Warrants still exist although at a diminished level. Probably more dilution coming. One thing I?m not sure about is the CEO. He "retired" from what has become ELOT, then he shows up in VION. Thirdhand info says he was not the best CEO when he ran the other company. Then again time will tell. Jim

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