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Biotech / Medical : Cistron Biotechnology(CIST)$.30

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To: Chris W. who wrote (2522)1/21/2000 12:13:00 PM
From: Walter Morton   of 2742
 
Issued/Filed Dates: May 14, 1999 / Nov. 2, 1998

The present invention concerns compositions comprising an encapsulated immunomodulator, such as cytokines and lymphokines, that is useful as an adjuvant for stimulating an immune response when administered to a human or animal. For example, a lymphokine such as IL-1.agr. or IL-1á can be used as an immunomodulator encapsulated in a matrix according to the invention. The encapsulated composition can include a vaccine antigen, such as whole inactivated or attenuated virus, recombinant or synthetic peptides, and other antigenic materials. The encapsulation matrix can be natural orsynthetic. The present invention also pertains to the use of an encapsulated immunomodulator in a human or animal as an adjuvant to increase immune responses to an antigen or other material to which an immune response is desired.

patents.ibm.com
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