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Pastimes : son of T/FIF
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To: scaram(o)uche who wrote (485)1/22/2000 8:54:00 PM
From: Torben Noerup Nielsen  Read Replies (1) of 673
 
Richard,

NABI deserves at least honorable mention. Just take a look at the chart for this last week. It's enough that I no longer believe it was just because of the nicotine vaccine story that ran although that may have caused some people to take a closer look.

In my opinion, Nic-VAX is a fantastic ace in the hole if it works. And it's known to work on monkeys so it ought to work just fine on humans.

But the real potential here lies in their Staphyloccus Aureus vaccine. Yes, other groups are working on that too, but NABI has a patent that allows only them to make a trivalent vaccine. Everyone else has to make do with the bivalent one. And I think this is a major plus since the additional strain adds coverage about 15% of coverage. Given the rise of nosocomial infections, vaccination against S. Aureus might become part of standard preparation for non-emergency surgery. Or for any hospitalization for that matter. Consider women who're giving birth; there are a lot of them and most go into a hospital or clinic. As far as I know, it's safe to give them vaccines once they enter the 3rd trimester and it would seem a reasonable precaution if there were a safe vaccine. The notion of pregnant women being a group that's particularly at risk for nosocomial infections just popped into my head. Any obstetricians here who might know if this is true?

And then there's bovine mastitis. I've been looking at all the information I can find here and I really think it's a major market. There are a lot of cows out there and dairy farming is *big* business. In Europe too.

Thanks, Torben
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