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Biotech / Medical : Agouron Pharmaceuticals (AGPH)

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To: margie who wrote (635)4/25/1997 1:35:00 PM
From: Jorgen Jensen   of 6136
 
To all,

Perhaps this announcement has something to do with the carnage:

Wednesday April 23 6:54 PM EDT

Merck( Merck & Co Inc ) says working on new anti-AIDS therapy

BRANCHBURG, N.J., April 23 (Reuter) - Merck and Co Inc said on Wednesday researchers were working on a new
combination therapy to fight HIV, the virus that causes AIDS.

The new treatment combines Merck's Crixivan, a protease inhibitor, and a compond known as DMP-266, being developed
by a DuPont Co ( E.I. Du Pont De Nemours & Co (DuPont) )-Merck joint venture, Merck researchers told shareholders at the
company's annual meeting.

DMP-266 is non-nucleoside reverse transcriptase inhibitor.

Edward Scolnick, president of Merck Research Laboratories, said the new combination is "what we believe is a new regimen
for treating HIV."

In preliminary studies, the new dual therapy had shown to be more effective than triple therapies using a protease inhibitor in
combination with two older-line anti-HIV drugs, he said.

The triple therapies have been shown effective in sharply reducing the level of HIV in the bloodstream.
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