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To: steve mamus who wrote (4376)	3/8/2000 3:49:00 AM
From: Jill	Read Replies (1) of 8096

Thanx Steve...Here's a URL that will speed up your research: it's all about TCLN (very promotional of course) geocities.com Here's a few excerpts: TCLN HAS 6 BIG TECHNOLOGIES! TNT (Cotara) = TUMOR NECROSIS THERAPY ? Monoclonal antibody that can target ALL solid tumor cancers. Attach whatever you want to TNT, and it will carry it with pinpoint accuracy to the tumor site. VTA = VASCULAR TARGETING AGENTS ? -Technology that can target ALL solid tumor cancers. Used to carry blood-clotting agents precisely to the tumor. These clotting agents cause tumor only blood clots, thus choking off their blood supply resulting in tumor death. VEA = VASOPERMEATION ENHANCEMENT AGENTS -- Monoclonal antibody that carries compounds that cause the blood supply of the tumor to increase, thus allowing more chemotherapy drugs to enter the tumor and kill it. 2C3 = ANTI-ANGIOGENESIS AGENT ? Monoclonal antibody that blocks VEGF receptors on tumor vessels, thus halting tumor growth. LYM-1 = Monoclonal antibody used in the treatment of intermediate and high-grade Non-Hodgkin?s B-cell lymphoma. MAT = Technology that allows ALL monoclonal antibodies to work better. I find the vascular targetting agents interesting.

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