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Non-Tech : Le coin des francophones
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To: lapiastre who wrote (16024)4/6/2000 8:33:00 AM
From: lapiastre  Read Replies (1) of 77509
 
CRA est actuellement sur CNN. · surveiller aujourd'hui

ROCKVILLE, Md.--(BW HealthWire)--April 6, 2000--Celera Genomics (NYSE:CRA - news), a PE Corporation business,
announced today that it has completed the sequencing phase of one person's genome and will now begin to assemble the
sequenced fragments of the genome into their proper order based on new computational advances. Celera began to sequence
the human genome seven months ago in September 1999. In addition to assembly, the company will now focus on annotating
the sequence information and collecting additional data on genetic variations.

Celera's whole genome shotgun sequencing technique involves sequencing from both ends of the double stranded cloned DNA.
Celera's accurately paired clone end sequences are a key tool for assembling the genome much more completely than single
stranded sequencing methods allow at comparable levels of sequence coverage. Celera's paired end-sequencing strategy, as
part of the whole genome shotgun sequencing technique, has now produced sequence pairs from clones that cover the human
genome 11 times. The company believes that 99% of the human genome is represented in the cloned DNA.

Celera's whole genome sequencing strategy has been validated by the recent publication of the Drosophila melanogaster (fruit
fly) genome, the largest genome to be sequenced and assembled to date. Drosophila is a very important model for human
biology and medicine. After assembly and annotation, the non-repetitive regions of the Drosophila genome have greater than 99.99% sequence accuracy.

ca.biz.yahoo.com
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