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Biotech / Medical : Sangamo Therapeutics, Inc. SGMO
SGMO 0.505-4.8%12:21 PM EST

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To: Mike McFarland who wrote (9)4/9/2000 6:28:00 AM
From: scott_jiminez  Read Replies (1) of 368
 
Mike - some more ZFP background info and perhaps a general approach towards accessing essential basic science in the future.

A while back I posted this on the Ariad thread: Message 12761380

I searched for 'Zinc finger' on PubMed and randomly selected this abstract as an example ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10753724&dopt=Books Just click on the zinc finger link for some background from Alberts et al.

Specifically,
1. Introduction to the control of gene expression ncbi.nlm.nih.gov:80/books/mboc/mboc.cgi?code=090201782446183

and the ninth item down in the outline,

2. There Are Several Types of DNA-binding Zinc Finger Motifs ncbi.nlm.nih.gov:80/books/mboc/mboc.cgi?code=09020921547924

Reading this entire chapter should give you a reasonable jump start towards understanding Sangamo's science.
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