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Biotech / Medical : Celera Genomics (CRA)

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To: gao seng who wrote (308)	5/8/2000 8:32:00 PM
From: allen menglin chen	Read Replies (1) of 746

Now BBC is recycling DT's news w/ the "wrong" title -- the links below comes w/ 2 nice drawings. How can u have a "complete" gene map when the whole genomic map is not done yet?! And DT has done 60K genes, w/ 40+K still in progress. news.bbc.co.uk Complete human gene map claimed Raw data from chromosome 21 By BBC News Online science editor Dr David Whitehouse A "dark horse" private company in the US is claiming to have won the race to produce a complete gene map of humans. At the same time publicly-funded scientists in Germany and Japan have passed another milestone in decoding human chromosome 21. The private company Doubletwist is a relative newcomer in the genome race and claim to have obtained the first "working draft" of the entire human genome. They say they did this by analysing publicly-available data using Sun workstation computers. The company believes its rough draft comprises the 105,000 genes of the human genetic blueprint. Surprise entry "The Human Genome Project has done a tremendous job of providing the primary sequence of more than 80% of the genome to date. We have built upon this accomplishment by processing this data to reveal its most important information - the genes," said John Couch, Chairman and CEO of DoubleTwist. Doubletwist's entry into the genome race comes as a surprise to genetic onlookers as it was thought that the race to complete the human genome was between the privately-funded Celera Genomics corporation and the publicly-funded Human Genome Project (HGP). Three weeks ago, Celera's CEO Craig Venter announced that his company had obtained the entire gene sequence of a human but had not yet assembled it into the correct order. He added that it would only take them a few weeks to complete that task. Sequencing landmark The decoding of chromosome 21 is a significant achievement for the HGP. It will be published in the journal Nature. It comes as rumours circulate in the scientific community that an official announcement that the entire human genetic blueprint has been sequenced is just days away. The announcement could be made at an important gathering of genome scientists on Thursday at Cold Spring Harbour Laboratory, Long Island, US. Chromosome 21 is the smallest human chromosome comprising less than 1.5% of the entire human genetic code. Extra copies of the chromosome result in Down's Syndrome, the most frequent cause of mental retardation. It affects one in 700 births. The scientists say that chromosome 21 has 33,546,361 base pairs of DNA arranged into 127 genes. Search BBC News Online Advanced search options BBC ONE TV NEWS WORLD NEWS SUMMARY See also: 17 Apr 00 \| Sci/Tech Human genome: A private vs public battle 03 Dec 99 \| Sci/Tech Book of life: Chapter one 23 Nov 99 \| Sci/Tech Genome race hots up 14 Apr 00 \| Sci/Tech Human chromosome code obtained 10 Apr 00 \| Sci/Tech Caution urged over genome hype Internet links: German Human Genome Project Japan Human Genome Project Doubletwist Celera Genomics Nature The BBC is not responsible for the content of external internet sites Links to other Sci/Tech stories are at the foot of the page.

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