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Technology Stocks : John, Mike & Tom's Wild World of Stocks
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To: John Pitera who wrote (1305)6/12/2000 7:26:00 AM
From: wlheatmoon  Read Replies (1) of 2850
 
The human immune system perceives the mouse antibody as a foreign entity in itself, so in order to get around the immune system response, scientists developed humanized antibodies - part human, part mouse molecules that isolate the disease-fighting, cell-binding region of the mouse (and a few key amino acids) combined within the framework of a human antibody.

interesting concept, but not without some potential problems. the human body's immune system is sophisticated and any part of a mouse's protein (antibodies are proteins) may eventually elicit an immune reaction. the reaction may not occur immediately, but could develop over time.

eventually, drug companies should be able to make complete HUMAN antibodies--either through some special cell culture system to grow large numbers of B cells.

for now, this technique can bridge that gap.

however, let it be noted that pinkie don't mind mouse antibodies...-g-
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