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Strategies & Market Trends : Biotechnology Cancer Cures

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To: Jim Oravetz who wrote (161)6/27/2000 7:51:00 AM
From: Jim Oravetz  Read Replies (1) of 226
 
TWO-DRUG COMBINATION THERAPY SHOWS PROMISE AGAINST MELANOMA
Melanoma researchers at University of California, San Diego (UCSD) have developed a new drug-combination therapy that has proven in Phase II clinical trials to be significantly better at extending patients? lives than any other drug therapy.

The two drugs, tamoxifen and cisplatin, are commonly used chemotherapeutic agents. Interestingly, neither drug, when used alone, has proven effective against melanoma.

?For reasons that aren?t yet clear, this combination creates a synergism that is highly toxic to melanoma cells,? said Edward F. McClay, M.D., principal investigator of the study and director of the Melanoma Care Unit at UCSD Cancer Center.

Results of the clinical trial are being published in the July 2000 issue of the British Journal of Cancer. The clinical trial was based upon earlier laboratory work in which McClay and colleagues first identified this synergistic interaction. snip....

health.ucsd.edu

Jim
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