ADVR should be getting a lot of attention in the coming weeks / months....I'm a buyer in the 40s
Applies to -- ADVR
Advanced Viral Research Corp. Cites Influence of 'Product R' On Opportunistic Infections
Advanced Viral Research Corp. Cites Influence of 'Product R' On Opportunistic Infections
YONKERS, N.Y., Jun 29, 2000 (BW HealthWire) --
Dr. Shalom Z. Hirschman Discusses Recent Research on Human Papilloma Virus and Dire Need for Effective Drugs in New Online Forum
In his second online forum on Advanced Viral Research Corp.'s (OTCBB:ADVR) Web site -- adviral.com -- company President and CEO Dr. Shalom Z. Hirschman discusses the dire need for more effective drugs to treat the "opportunistic" infections that often develop in persons with AIDS.
Opportunistic infections are the most devastating complications in people with AIDS. They occur as a result of the destruction of immune function by infection with the human immunodeficiency virus (HIV). Human papilloma viruses (HPV) are among the most common infections for which no therapy exists, or for which the existing therapy is only marginally effective and fraught with severe toxic side effects.
As Dr. Hirschman writes, "In persons whose immune systems have been compromised, these infections become much more severe and can be life threatening. At present, no effective drug has been approved (by the FDA) for the systemic treatment of disseminated HPV infection."
However, recent research by scientists at the Advanced Viral Research Institute has shown that Product R, an experimental drug being developed by the company as a broad spectrum antiviral, interferes with the actual replication and growth of HPV in cell culture. Earlier research by the company demonstrated that Product R interferes with the expression of a key protein implicated in the development of cervical cancer (the product of the E7 gene of HPV subtype 18).
Writes Dr. Hirschman, "These results indicate that Product R may be useful in the treatment of disseminated human papilloma virus infection and in inhibiting the development of cervical cancer. Indeed, these preliminary clinical results suggest that Product R may be an effective non-toxic drug for both systemic and topical therapy of disseminated HPV infection in people with AIDS."
To read the complete text of current and previous installments of "Dr. Hirschman's Forum," visit adviral.com.
Shalom Z. Hirschman, M.D., joined Advanced Viral Research Corp. as president and CEO following a 28-year affiliation with The Mt. Sinai School of Medicine and The Mt. Sinai Hospital. During his tenure there, Dr. Hirschman held several academic positions, including Director of the Division of Infectious Diseases, Professor of Medicine, and Vice Chairman of the Department of Medicine. He spent seven years at the National Institutes of Health in Bethesda, MD; he has been published in many peer-reviewed journals, including THE NEW ENGLAND JOURNAL OF MEDICINE, NATURE and SCIENCE, and founded one of New York City's first and most active AIDS treatment and research centers.
About Advanced Viral Research Corp.
Advanced Viral Research Corp., based in Yonkers, New York, is a biopharmaceutical firm committed to researching, developing and bringing to market new, effective therapies for viral and other diseases, which will lead to the alleviation of human suffering and diseases worldwide. Its flagship drug, Product R, is a non-toxic immunomodulator that has been shown to have beneficial therapeutic effects against viral diseases such as AIDS.
Note: This news release contains forward-looking statements that involve risks associated with clinical development, regulatory approvals, including application to the FDA, product commercialization and other risks described from time to time in the SEC reports filed by ADVR. Product R is not approved by the U.S. Food and Drug Administration or any comparable agencies of any other countries.
CONTACT: Bratskeir & Company Mike Rosen 212-679-2233 mrosen@bratskeir.com
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KEYWORD: NEW YORK INDUSTRY KEYWORD: MEDICAL BIOTECHNOLOGY PHARMACEUTICAL
Applies to -- ADVR -- DIPL
Advanced Viral Research Corp. to Present At 38th Annual Meeting of the Infectious Diseases Society of America
Advanced Viral Research Corp. to Present At 38th Annual Meeting of the Infectious Diseases Society of America
YONKERS, N.Y., Jun 27, 2000 (BW HealthWire) --
Scientists to Discuss Antiviral Properties of Product R
Advanced Viral Research Corp. (OTCBB: ADVR) today announced that scientists from the Advanced Viral Research Institute will give two presentations at the 38th Annual Meeting of the Infectious Diseases Society of America (IDSA), taking place September 7-10, 2000 in New Orleans, LA.
Led by Dr. Wenlin Huang, Advanced Viral Research Institute scientists will discuss various aspects of the antiviral properties of Product R, a non-toxic peptide nucleic acid (PNA) immunomodulator the company is developing as a broad-spectrum antiviral drug. Details regarding the presentation will be announced in late August or early September.
"We are honored to have an opportunity to present our most recent research findings at such a prestigious forum," said Shalom Z. Hirschman, MD, president and CEO of Advanced Viral Research Corp. "In addition, our colleagues in Argentina have reported progress on our phase one clinical studies with Product R. We continue to move with a determined focus toward our expectations of beginning to file Investigational New Drug applications with the U.S. Food and Drug Administration later this year. We are making strides in advancing our mission to improve the quality of life of people suffering from a variety of debilitating diseases."
Product R shows promise for the treatment of viral infections such as AIDS and Human Papilloma Virus (HPV), and autoimmune diseases like rheumatoid arthritis. Advanced Viral Research Corp. laboratory studies have shown that Product R inhibits the production of both the CCR5 and CXCR4 chemokine receptors, the key cellular co-receptors for the human immunodeficiency virus (HIV).
The Infectious Diseases Society of America represents more than 5,500 physicians, scientists and other health care professionals who specialize in research and clinical aspects of infectious diseases. The Society's mission is to promote and recognize excellence in patient care, education, research, public health and the prevention of infectious diseases.
About Advanced Viral Research Corp.
Advanced Viral Research Corp., based in Yonkers, New York, is a biopharmaceutical firm committed to researching, developing and bringing to market new, effective therapies for viral and other diseases, which will lead to the alleviation of human suffering and diseases worldwide. Its flagship drug, Product R, is a non-toxic immunomodulator that has been shown to have beneficial therapeutic effects against viral diseases such as AIDS.
Note: This news release contains forward-looking statements that involve risks associated with clinical development, regulatory approvals, including application to the FDA, product commercialization and other risks described from time to time in the SEC reports filed by ADVR. Product R is not approved by the U.S. Food and Drug Administration or any comparable agencies of any other countries.
CONTACT: Bratskeir & Company Mike Rosen, 212-679-2233 mrosen@bratskeir.com
URL: businesswire.com Today's News On The Net - Business Wire's full file on the Internet with Hyperlinks to your home page.
Copyright (C) 2000 Business Wire. All rights reserved.
Distributed via COMTEX. -0-
KEYWORD: NEW YORK INDUSTRY KEYWORD: BIOTECHNOLOGY MEDICAL PHARMACEUTICAL PRODUCT |