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Biotech / Medical : Celera Genomics (CRA)
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To: John Solder who wrote (547)7/10/2000 3:39:11 PM
From: John Lacelle  Read Replies (2) of 746
 
John,

I think this whole human genome thing is blown way out
of proportion. Even if you have the genetic sequence
for a human gene, you are still a long way from having
a "cure" for any disease for that might occur from a
"defective" version. Consider for example the HIV virus,
that which causes the disease of AIDS. I know the sci-
entist who used X-ray defraction to determine the stru-
cture of HIV's reverse transcriptase. She did this work
as a post-doc in the early 90's. If you can make a drug
that would disable this enzyme, you could "cure" AIDS.
Yet, even with the structure of reverse transcriptase
being known, wonder drugs are still not available. I'm
afraid that developing therapies for "defective" human
genes is going to be a very expensive, long term project.
Furthermore, with the case of Celera, they will probably
not be able to hold the rights to any gene they have
cloned and they compete directly with the human genome
project, a completely free database available to anyone
with a computer and an ISP.

-John
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