A gene that can predict the severity of rheumatoid arthritis... to be published in the September 2 issue of the LANCET
Monday, August 28, 2000
Gene research may promise new arthritis treatment
TORONTO: Canadian researchers said they have identified a gene that can predict the severity of rheumatoid arthritis, a discovery that could lead to earlier treatment and possibly a cure for the debilitating joint disorder,reports UNI.
The research, funded in part by Canada's arthritis society arthritis research centre, focused on the ifn gamma gene, which is important in controlling the body's immune system.
Researchers said yesterday that the severity of a person's rheumatoid arthritis depends on differences found in the ifn gamma gene.
''We believe the gene identified operates by controlling the degree of joint inflammation. It is the most powerful indicator currently recognised for predicting the severity of rheumatoid arthritis,'' said dr. Abbas khani-hanjani of the immunology laboratory at Vancouver general hospital in a statement.
The study, results of which were leaked to the national post on Wednesday, will be published in the September 2 issue of the Lancet medical journal.
The arthritis society said the discovery will enable doctors to refine their treatment efforts at an early stage when symptoms are still mild, preventing the destruction of cartilage, bone, tendons and ligaments, which can lead to severe deformity and debilitating pain.
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