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Biotech / Medical : XOMA. Bull or Bear?
XOMA 32.40+1.8%9:44 AM EST

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To: manfredhasler who wrote (14744)9/19/2000 9:27:13 AM
From: aknahow  Read Replies (2) of 17367
 
When you began posting you spoke at great length about the scientific method and the danger of anarchy. Now even though you also said you would read the entire article, you continue to cast aspersions on what the investigators did based on your suspicious.

Seems a bit fishy, at least to me.

Are you aware of the fact that of the 34 children who died on 16 had received the full treatment? Eighteen died before receiving all of scheduled test drug/placebo?

Four of the subjects receiving Neuprex died and 12 of those receiving the placebo died. but now of course the sample is way too small to be statistically conclusive, under standard FDA requirements.

But Subpart E and orphan drug status was granted to XOMA. Cacaito says the surrogate endpoints not met. But the major endpoints were except not in a statistically significant way. So even though their were 1/3 the deaths in the treated group than in the placebo group and you post, <<<<<" My suspicion is that the
investigators did not care about the proper patient inclusion and just continued to enroll as many patients
as suggested by the study protocol. To the costs of the company.">>>>>>

How does including 18 children that died before treatment support your suspicion that "investagotors did not care about proper patient inclusion"? Is your suspicion based on scientific thinking?
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