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Biotech / Medical : Neuroscience

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To: nigel bates who wrote (122)	11/2/2000 6:36:11 AM
From: scott_jiminez	Read Replies (1) of 278

Nigel - I saw that article during my weekly bi-monthly review of JN...and I skimmed over it. I draw your attention to the key phrase (IMO...having NOT read the article): 'purine-sensitive' pathway. This is very different than a 'purine-dependent' pathway: countless intracellular pathways are 'purine-sensitive'. Not only do these types of claims about magic bullets/master switches for axonal regeneration come and go like ants (and all the usual concerns about ectopic sprouting are still extant), but there were many more interesting articles in this issue of the journal anyway. The only reason this 'news' is being discussed on SI is because THE COMPANY has released a bulletin to drive its PR machine (I'm not picking on BLSI here - every biotech company does it. The practice invariably detracts from an objective discussion of the science.) Nevertheless I'll go back and read it....and tell you about some alternative articles that really deserve your attention. [BTW - the reason that I don't comment more on the news articles placed on this thread is...time. To wit, to give the current article a fair review, and to present a reasonable analysis to a (largely) non-scientific audience, I will spend 2-3 hours in preparation.]

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