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Biotech / Medical : Trickle Portfolio

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To: tommysdad who wrote (134)11/28/2000 11:55:16 AM
From: Dr. Voodoo  Read Replies (3) of 1784
 
Nice List.

This is kinda like Christmas Shopping...Hmmm Maybe my boss will find out!

Some thoughts from another angle. I'm a little more expensive so I'd probably take about 5-6M in start up:

For my 20 bench chemists I'd want about 1-2 technicians each depending on how good they are:

10 Quest Synthesizers from Argonaut. 300K

1 Irori Tagging system with about, and the washing machine machine that goes with it. ~150K

5,000 tags to go with it 50K.

Cans, stations etc. 30K

Look around for a high throughput synthesizer I liked, 400K.

Partial to the HP LC/MS systems myself. Gilsons for them all too. Probably need 2-3 of em, to run every compound over LC/MS. 480K

For sample handling I'd pick up either a Bohdan or HP liquid handling robot, damn biologists want everything done for them.--100K

For high througput weighing I'd pick up the Bohdan Weighing station for 80K.

For analytical-semiprep HPLC's I'd need about 2 Waters 600 systems with PDA detectors at 50K each, and 2 Waters 600 systems 30K plus 4 Sedere ELS detectors to run in tandem or solo at 15 K each. 220K--Each can run at 20 mL/min, or another 1K gets ya 30ml/min, more than enough to get 100 mgs in a pinch.

Columns and stuff 30 K

Like 500K for the Varian NMR, or could easily go with Bruker, gotta chuck in an autosampler and pick up a magic angle probe and a few other odds and ends..650K

FTIR 50K

For HiRes MS I'd send it out.

For screening, I'd look into one of those fancy ion-cyclotron 7T jobbies and I'd hire me an expert to put it together. 1-2M

I too would find a way to steal my license from MDL. Gotta get the basic stuff like modeling etc plus ACD. Those guys are too proud.

Rotovaps computers etc I think I pretty much agree with what ya got.

I would buy a few compounds to get me on the dance floor. I want to cherry pick mine. Free is OK.

I'd need about 100 K or so per year to handle the chemical informatics, and freezers to put all this stuff I made.

FOR BIOLOGY.

Since my nice chemists were kind enough to put my stuff in plates all mapped out.

I need about 500 K to give to Amersham for running Scintilation proximity assays.

I need about 300 K for robotics to handle my part of the liquid handling.

I need about 20 biologists to find new targets and design and run new assays.

I need a huge pile of money for plastic junk I'm only going to throw away.

V
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