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Biotech / Medical : Neuroscience

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To: Jim Oravetz who wrote (143)	12/19/2000 12:37:32 PM
From: Jim Oravetz	Read Replies (1) of 278

Axonyx Starts Phase II Trial On Potential Alzheimer's Drug Dow Jones Newswires NEW YORK -- Axonyx Inc. (AXYX) started a Phase II clinical trial for Phenserine, its lead drug candidate for the treatment of Alzheimer's disease. In a press release Tuesday, Axonyx said the trial is an important step toward obtaining approval to market the drug. The Phase II study is double blind and designed to determine the efficacy and safety in patients with the clinical signs of mild to moderate Alzheimer's disease. The first patients have been randomized and will receive either active or placebo treatment. The study is being conducted in the U.S. at two clinical sites. Study results are expected toward the end of the second quarter. In September, Axonyx said a multiple dose Phase I trial of Phenserine demonstrated that the Alzheimer's drug is safe, well-tolerated and inhibits red blood cell enzyme acetylcholinesterase. Company Web site: axonyx.com

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