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Biotech / Medical : COMPUTERIZED THERMAL IMAGING (COII)- research only

CIO 6.960

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Dec 26 3:59 PM EST

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To: chirodoc who started this subject	1/1/2001 11:43:39 AM
From: chirodoc	of 256

can biopsy increase cancer risk? CONCLUSION: Seeding or implantation was suspected as the cause of local recurrence in 7% (3/44) of the invasive cancers which did not receive radiotherapy. Acta Radiol 2000 Sep;41(5):435-40 Related Articles, Books, LinkOut Local breast cancer recurrence caused by mammographically guided punctures. Thurfjell MG, Jansson T, Nordgren H, Bergh J, Lindgren A, Thurfjell E Department of Oncology, Radiology and Clinical Immunology, Uppsala University Hospital, Sweden. PURPOSE: To evaluate the risk of needle track seeding or tumor cell implantation as the cause of locally recurrent breast cancer after breast conserving surgery. MATERIAL AND METHODS: We reviewed recurrences from a consecutive series of 303 clinically nonpalpable breast cancers treated with breast conserving surgery after pre-operative localization. The median mammographic follow-up was 5.4 years. The suspicion of seeding or implantation was based on the location of the recurrent lesion in comparison with the needle path in two orthogonal mammographic projections. Pre-operative percutaneous biopsies had been done in 71% (214/303) of the cases. Postoperative radiotherapy was administered to 82% (194/238) of the invasive cancers and to 28% (18/65) of the ductal cancers in situ (DCIS). RESULTS: Locally recurrent cancer occurred in 11% (33/303) of the cases. Radiotherapy demonstrated a protective effect from relapse among invasive cancers but not for DCIS. Seeding or implantation was suspected in 3 recurrent invasive cancers which had not been subject to radiotherapy. The histopathological diagnosis of the primary cancer and the recurrent cancer were the same in these cases: adenoid cystic, mucinous and tubuloductal cancer. CONCLUSION: Seeding or implantation was suspected as the cause of local recurrence in 7% (3/44) of the invasive cancers which did not receive radiotherapy

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