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Biotech / Medical : IDPH--Positive preliminary results for pivotal trial of ID

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To: Brad C. Dunlap who wrote (942)6/3/1997 11:49:00 AM
From: Richard Belanger   of 1762
 
Brad, regarding the wide range of estimated FY98 earnings, it appears that C2B8 will be essentially unchallenged as a treatment for relapsed low-grade or follicular NHL for roughly 14-16 months following approval (assuming BLA for Coulter's Bexxar is filed and approved on schedule). Can we assume, then, that the major uncertainty involves the extent that C2B8 will be accepted as a treatment for other-than-relapsed NHL?

Regarding the sustainability, Bexxar has been shown to be more efficacious than C2B8, and I would imagine be indicated for cases of large tumor mass. However, we do not yet know how Bexxar will stand up against Y2B8. With respect to the radiological properties (Bexxar's Iodine-131 vs. Y2B8's Yttrium-90), I like what I see in the Idec product.

Thanks in advance.

Rich
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