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Biotech / Medical : SNAP
SNAP 7.800+2.6%Oct 31 9:30 AM EDT
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To: Mike McFarland who wrote (101)2/2/2001 11:08:53 PM
From: Mike McFarland  Read Replies (1) of 124
 
12/11/2000 Synaptic Pharmaceutical Awarded Patent For The Alpha Adrenergic 1B and 1D Receptors
12/04/2000 Synaptic Pharmaceutical Identifies A Novel Approach to Controlling the Spread of Certain Types of Cancers
synapticcorp.com

__________________________________________________
Bioorg Med Chem Lett 2000 Dec 18;10(24):2705-7
Determination of the relative and absolute stereochemistry of a potent and alpha1A-selective adrenoceptor antagonist.
Lagu B, Wetzel JM, Forray C, Patane MA, Bock MG
Department of Chemistry, Synaptic Pharmaceutical Corporation,

The binding affinities and selectivities of antagonists 1-4 for the alpha1A-adrenoceptor are dependent
on the stereochemical orientation of the groups at the C-4 and C-5 positions of the oxazolidinone ring.
The unambiguous assignment of the relative and absolute configurations of the diastereomers of
SNAP 7915 (1) is reported.

A couple of patents issued in December
synapticcorp.com
--Oxazolidinones as Alpha 1a Receptor Antagonosts

I do not remember much of anything from my college chemistry.
This is probably a good time to step off the thread...maybe somebody
else on SI owns a little SNAP. And after my nastygram in the previous
post, I'm probably in the doghouse for awhile longer.

Still long some SNAP, but no clue. Just stubborn and not willing
to pay the commission to lighten up on the shares.
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