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Biotech / Medical : Biotech Valuation

CRSP 54.58

-1.0%

Nov 10 3:59 PM EST

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To: Biomaven who wrote (3250)	3/30/2001 7:33:48 PM
From: scaram(o)uche	Read Replies (3) of 52153

Peter...... it's perfectly clear........the MC4 receptor is expressed in both the spinal cord and the brain thingie, and the neurons containing the alphaMSH peptide, the so-called hypothalamic POMC neurons, send nerve thingies to both regions. Agonist activation of the MC4 receptor, at each of these loci, results in deprivation of food intake and energy expenditure, and in control of blood flow to the really good stuff. MRK patents on MC4 agonists focus on the ED aspect, perhaps to get around the MLNM use patent for the MC4 receptor and antiobesity agents. This is my educated thesis.

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