Thanks JB.
<<‘If it works in humans like it did in the mouse, I would like it for myself.’ >>
Not me. My BMI Is –15%, so I will look like skeleton in 3 months.
<<In the knockout mouse, said Wakil, very little fat was put into storage. He said the knockout mouse had a slightly higher temperature than the normal mouse, possibly as a result of high fat metabolism.
Wakil said the lack of fat stored also sends an appetite signal to the brain, commanding the animal to eat more. He said this may explain why the knockout mice tended to eat up to 40 percent more than the control mice.>>
Higher metabolite rate have to be compensate with more food, which will be burned faster, which will require more food, which... No thanks! Where will al this energy end?
+90% of all obese [EATING disorder] population are obese because they eat without control, they eat *like a pig*. They do not have effective SATIETY signal, or they do not fill that way. This approach (ACC2) may be contra-productive, imo. Food chain companies would love it, not those who need new better medicine. Can you image 300# person whose heart-beat rate increase 15%? Or something else???
Axokine main advantage over ANYTHING which is today on market or at R&D stage is: SLOW, GRADUAL, but SUSTAIN reduction in body weight WITHOUT triggering ANY contra-balancing mechanism. REDUCTIN of the FOOD INTAKE and better control of the ENERGY EXPENDITURE. Remember this in five years.
Few investors do not think so. They are happy with small gain and selling REGN now. Contrary, I will not rest until REGN MC reach multiple-10X today level, or maybe bit more.
Miljenko |
