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Biotech / Medical : Biotech Valuation
CRSP 51.32-1.7%12:25 PM EST

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To: scaram(o)uche who wrote (3967)6/3/2001 9:28:46 AM
From: Biotech Jim  Read Replies (2) of 52153
 
Abarelix weaknesses may include the monthly injections, loss of masculine secondary sex characteristics (not a big deal if androgen-dependant cancer is to be eliminated) and the lack of much published literature on its activities.

Others are working on nonpeptide GNRH antagonists. A look at issued US patents shows that Merck has an extensive effort with over 20 issued patents, M. Goulet appears to be heading this effort. In my limited analysis, MRK does not seem to have made any announcements here, but this is not unusual for them especially after the MK 869 fiasco. I would put a significant bet that they are easily in the lead here. Agouron and of course NBIX have limited efforts here as well. S. Sealfon at Mount Sinai holds a receptor patent.

BJ
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