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Biotech / Medical : LEXG-Lexicon Genetics
LXRX 1.250-12.6%Nov 7 9:30 AM EST
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To: tuck who wrote (65)6/16/2001 3:25:42 PM
From: nigel bates  Read Replies (1) of 254
 
I'll sniff around, but I'm afraid I have no idea. My biotech knowledge might be compared to a very shallow puddle of reasonable size. Any shallower, though, and it would evaporate...

I've only a small position in LEXG and haven't paid it as much attention as I might. Turned up this on the DGEN website -

Deltagen is an exclusive worldwide licensee of a secreted protein gene trap from the University of Edinburgh that identifies genes that code for secreted proteins and simultaneously enables the production of knockout mice to determine the in vivo function of these genes. This secreted gene trap technology will work in all cell types. However, when the system is employed in mouse ES cells, the resultant ES cells containing the ES deletion can be used to rapidly generate knockout mice.
We believe that the benefits of our Gene Trap technology are the ability to:

* identify rarely expressed genes;
* move directly to in vivo analysis in the mouse eliminating the need for cell-based experiments which require protein or antibody production to define function;
* directly define the role of cell surface receptors and function in all cell types; and
* identify key secreted proteins in a variety of physiological conditions.

Has LEXG got anything directly comparable which works backwards to the gene ?
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