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Biotech / Medical : Supergen (supg)

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To: Biomaven who wrote (106)	7/18/2001 10:24:05 AM
From: Mike McFarland	Read Replies (1) of 124

GW posted a link to a news report on decitabine on the Indications_Cancer thread. Supergen has followed up today by doing a press release. Decitabine's unique mechanism of action, the regulation of methylation of DNA, allows the genes to be switched back on, so that the cells are once again sensitive to the effects of the chemotherapy. So...tumor suppressor genes are back on, or DNA repair enzymes are back on? Joe says "unique"...is that so? incyte.com interferon-resistant tumors could be made susceptible to the drug by treating them with decitabine Can a bioscientist help refine this query? google.com

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