Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 206.54

+3.2%

Jan 9 9:30 AM EST

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To: Henry Niman who wrote (3702)	6/23/1997 11:32:00 AM
From: A.B.	of 32384

Hi Henry, the diabetes sceen gets increasingly intersting: SUGN announces a Novel Tyrosine Phosphatase inhibitor enhancing Insulin Action in vitro and lowers Plasma Glucose in orally-dosed db/db mice at the American Diabetes Association 57th Annual Meeting The data presented show that SUGEN's insulin phosphatase inhibitors both enhance glucose uptake as well as replicate downstream cellular events associated with normal insulin receptor signalling including lowering blood glucose levels and lipolysis, and up-regulating glycogen synthesis. Based on the compounds' mechanism of action, these drugs are expected to have potential application in Type II and Type I diabetes. biz.yahoo.com They are still in the early stages, IND is planned for end of 97. Cann you please comment how this approach compares to LGND's diabetes program? Thanks, mj.

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