Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 197.62

+0.1%

Dec 24 12:59 PM EST

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To: Kenneth E. De Paul who wrote (3737)	6/24/1997 7:33:00 AM
From: Henry Niman	of 32384

Kenneth, I uploaded the relevant LGND press releases. LGND is developing several retinoids (Targretin, ALRT268, LG100754) which activate RXRs which interact with activated PPARs (Rezulin and other TZDs activate the PPARs). The retinoids have applications for the treatment and prevention of type II diabetes (by turning on genes whose products overcome insulin resistance). The US diabetes market just grew by 2 million (due to the change in guidlines) and there is an increased emphasis on delay and prevention. Henry

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