T/FIF, a New Plateau Message Board

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Biotech / Medical : T/FIF, a New Plateau

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To: tuck who wrote (755)	11/27/2001 1:03:39 PM
From: scaram(o)uche	Read Replies (2) of 2243

Yeah, being cash-strapped is tough. Lots of large shareholders who could want to lighten up? Please let me know when it's time to buy it, and I'll sell something if I don't have cash. The portions that you highlighted with bold had no special meaning to me, other than that they had shown a molecular ass'n between SLAP-2 and a ubiquitin ligase. Was there a meaning inherent in the bolding? Ubiquitin ligases...... I don't know much about them. If there are different ligases for regulatory proteins like CDKs (take note, apostrophe police!!), then it might make sense. If not, it seems like just another anti-cancer approach that will land us in "selective toxicity" land. If anyone runs across any preclinical (mouse, etc.) data, please yell!

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