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To: Cal Gary who wrote (8644)	2/6/2002 3:17:22 PM
From: Cal Gary	Read Replies (1) of 14101

<font color=purple>Cool! "In reviewing the following information, it is important to keep in mind the realities of the drug discovery and development process. The U.S. system of new drug approvals is perhaps the most rigorous in the world. On average, it costs a company $359 million to get one new medicine from the laboratory to the pharmacist's shelf, according to a February 1993 report by the Congressional Office of Technology Assessment. It takes 12 years on average for an experimental drug to travel from lab to medicine chest. Only five in 5,000 compounds that enter preclinical testing make it to human testing. One of these five tested in people is approved." From: mhsource.com From page 9 of DMX's Annual Report 2001 Approximately five in 5000 potential drug compounds that enter preclinical testing ever make it to human trials, and only one of those five receives approval for sale, with the entire process spanning about 10 years. Despite these tremendous odds, Pennsaid Topical Solution advanced from clinical testing to market approval in less than seven years. <font color=purple>Odds getting better everyday. F.D.A.eh!

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