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Biotech / Medical : Biotech Short Candidates
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To: rkrw who wrote (195)3/17/2002 12:17:20 AM
From: tuck  Read Replies (1) of 897
 
rkrw,

Inhaled insulin: the safety problems are so bad it's not for years if at all? This seems a more pessimistic view than I've noticed you voice previously; what's the basis and does it extend to pulmonary delivery of other stuff/indications? Should we be discussing INHL and ARDM here seriously? You have mentioned exubera specifically, what I wonder is if you've learned or deduced something more general. And the PEG market is crowded and litigious, IMO.

Just what were the pulmonary side effects you alluded to back then? All I've found is from this INHL PR about the results presented at the ADA last year:

>>The frequency and nature of adverse events were comparable between groups. Pulmonary function tests showed no significant differences between patients receiving inhaled insulin versus those who received injections only. The most common respiratory clinical side effect reported among patients was cough, which was characterized as mild to moderate in nature.<<

As well as a serum antibody issue you didn't seem to think was important. Got a pointer to those side effects?

On my previous subject, DioMed, it turns out most of the financial info is in this 8-K about the reverse merger. Not used to those things, I at first thought the 8-K was just a PR till I noticed the size of it. Ratio of current assets to current liabilities not looking good at all, among other things . . . Can you say "upcoming dilution?" I knew you could.

sec.gov

Cheers, Tuck
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