T/FIF, a New Plateau Message Board

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Biotech / Medical : T/FIF, a New Plateau

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To: Biomaven who wrote (1118)	4/16/2002 10:03:22 AM
From: scaram(o)uche	Read Replies (1) of 2243

So, what have they got? (an analysis worth doing, given the cash to MC ratio, regardless that the cash is a long-term loan) Time on the learning curve, delivering small molecules to the lung. Time on the small molecule clinical learning curve, HCV patients. A potent RSV-spcific molecule where FDA has apparently said "make a phase I work in infants". The analysis by Cacaito in the VPHM thread is sufficient here. It's another tough indication to bite off. 50406 "backups" for HCV, one of which is scheduled for the clinic within eight months. We know that Wyeth/VPHM have studied at least two target molecules. A respected group of chemists that has proven that they can produce potent anti-virals. pleconaril, which FDA may still want available for compassionate use (immunosuppressed kids, etc.). VP68881, and a marked appreciation for how NOT to test it. Oodles of cash, and a serious issue with depression. Can anyone add to the list?

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